Apphia was a female Christian at Colossae (Philemon 1:2). She is addressed by the author of the New Testament epistle of Philemon, as "our sister." Some scholars speculate that Apphia might have been the wife of Philemon or related to Archippus. Colossae is an ancient Phrygian city that is now a part of Turkey.

Early church writings include a tradition that Philemon, Apphia, Archippus and Onesimus, all of whom are addressed in the epistle Philemon, were stoned to death during the reign of Nero, who was a Roman Emperor from 54 to 68 A.D.

The name means "increasing" or "that which is fruitful."

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